Synthetic Route of 3405-77-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 3405-77-4, 5-Methylisoxazole-3-carboxylic acid, introducing its new discovery.
Methods for increasing D-Serine concentration and reducing concentration of the toxic products of D-Serine oxidation, for enhancing learning, memory and/or cognition, or for treating schizophrenia, Alzheimer”s disease, ataxia or neuropathic pain, or preventing loss in neuronal function characteristic of neurodegenerative diseases involve administering to a subject in need of treatment a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt or solvate thereof:
- R1 and R2 are independently selected from hydrogen, halo, nitro, alkyl, acyl, alkylaryl, and XYR5;
- or R1 and R2, taken together, form a 5, 6, 7 or 8-membered substituted or unsubstituted carbocyclic or heterocyclic group;
- X and Y are independently selected from O, S, NH, and (CR6R7)n;
- R3 is hydrogen, alkyl or M+; M is aluminum, calcium, lithium, magnesium, potassium, sodium, zinc ion or a mixture thereof;
- Z is N or CR4;
- R4 is from selected from hydrogen, halo, nitro, alkyl, alkylaryl, and XYR5;
- R5 is selected from aryl, substituted aryl, heteroaryl and substituted heteroaryl;
- R6 and R7 are independently selected from hydrogen and alkyl; n is an integer from 1 to 6;
- at least one of R1, R2 and R4 is other than hydrogen; and
- at least one of X and Y is (CR6R7)n. D-serine or cycloserine may be coadministered along with the compound of formula I.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 3405-77-4. In my other articles, you can also check out more blogs about 3405-77-4
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem