In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 7063-99-2, name is Ethyl 5-phenylisoxazole-3-carboxylate, introducing its new discovery. Computed Properties of C12H11NO3
(Figure Presented) A series of 3-substituted and 3,5-disubstituted isoxazoles have been efficiently synthesized in moderate to excellent yields by the reaction of N-hydroxyl-4-toluenesulfonamide with alpha,beta-unsaturated aldehydes/ketones. This novel strategy is associated with readily available starting materials, mild conditions, high regioselectivity, and wide scope.
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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem