21169-71-1, Isoxazole-5-carboxylic acid is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 134 Isoxazole-5-carboxylic acid (1-{4-[3-chloro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-indol-1-yl]-benzylcarbamoyl}-cyclopropyl)-amide To a solution of 12.0 mg (0.106 mmol) of isoxazole-5-carboxylic acid in 2 mL of dichloromethane and 0.2 mL of N,N-dimethylformamide 15 mg (0.036 mmol) of 1-amino-cyclopropanecarboxylic acid 4-[3-chloro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-indol-1-yl]-benzylamide (Reference Example 9), 40.5 mg (0.106 mmol) of HBTU and 28.8 muL (0.43 mmol) of triethylamine were added. The mixture was shaken at room temperature for 18 h, then purified by column chromatography using n-hexane and ethylacetate as eluent to yield 17 mg (91%) of the title compound. MS (EI) 517.1 (MH+)., 21169-71-1
21169-71-1 Isoxazole-5-carboxylic acid 2060599, aIsoxazoles compound, is more and more widely used in various fields.
Reference£º
Patent; Richter Gedeon Nyrt.; Beke, Gyula; Benyei, Gyula Attila; Borza, Istvan; Bozo, Eva; Farkas, Sandor; Hornok, Katalin; Papp, Andrea; Vago, Istvan; Vastag, Monika; US2013/217702; (2013); A1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem