Archives for Chemistry Experiments of 33282-15-4

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4-Aminocyclopentenones were synthesized from readily available glycals and secondary anilines, with the aid of a Lewis acid-surfactant-combined catalyst. The reactions proceeded via a 4pi conrotatory electrocyclization, affording the corresponding 4-aminocyclopentenones in good yields with excellent diastereoselectivities.

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Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem