Downstream synthetic route of 13999-39-8

As the paragraph descriping shows that 13999-39-8 is playing an increasingly important role.

13999-39-8, 3-Amino-4,5-dimethylisoxazole is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

[19]; 2-(6-Chlorobenzotriazol-l-yl)-l,l,3,3-tetramethyluronium tetrafluoroborate was used in place of 2-(7-azabenzotriazol-l-yl)-l,l,3,3-tetramethyluronium hexafluorophosphate(V) as the coupling agent. The reaction product was purified using column chromatography on silica and a solvent gradient from methylene chloride to a 19:1 mixture of methylene chloride and methanol as eluent. The product gave the following characterising data :- 1H NMR Spectrum: (DMSOd6) 1.8 (s, 3H), 2.3 (s, 3H), 3.71 (s, 2H)5 3.78 (s, 3H)5 4.02 (s, 3H)5 6.53 (d, IH)5 6.89 (m, IH), 7.04 (d, IH), 7.23 (s, IH), 7.38 (d, IH), 8.77 (d, IH)5 9.43 (s, IH), 10.27 (br s, IH); Mass Spectrum: M+H+ 435., 13999-39-8

As the paragraph descriping shows that 13999-39-8 is playing an increasingly important role.

Reference£º
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2007/113565; (2007); A1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem