36958-61-9, 5-(Bromomethyl)-3-methylisoxazole is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
STEP A: ethyl 4-bromo-5-methyl-l-((3-methylisoxazol-5-yl)methyl)-lH-pyrazole- 3-carboxylate and ethyl 4-bromo-3-methyl-l-((3-methylisoxazol-5-yl)methyl)-lH-pyrazole- 5-carboxylate and [1124] To a mixture of ethyl 4-bromo-3-methyl-lH-pyrazole-5-carboxylate (0.331 g, 1.420 mmol) in DMF (10 mL) were added CS2CO3 (1.157 g, 3.55 mmol) and 5-(bromomethyl)-3- methylisoxazole (0.5 g, 2.84 mmol). The reaction mixture was stirred at room temperature for 20 hours and then diluted with water. The product was extracted into EtOAc. The organic phase was dried over Na2S04 and concentrated to give the title compounds as a crude mixture that was used without further purification (0.24 g).
36958-61-9, The synthetic route of 36958-61-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; CHERUVALLATH, Zacharia; ERICKSON, Philip; FENG, Jun; KOMANDLA, Mallareddy; LAWSON, John David; MCBRIDE, Christopher; MIURA, Joanne; MURPHY, Sean; TANG, Mingnam; TON-NU, Huong-Thu; WO2013/130855; (2013); A1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem