Final Thoughts on Chemistry for 1072-67-9

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1072-67-9, Name is 5-Methylisoxazol-3-amine, belongs to isoxazole compound, is a common compound. Quality Control of 5-Methylisoxazol-3-amineIn an article, once mentioned the new application about 1072-67-9.

A new series of alpha-aminophosphonates have been synthesized by a one-pot three-component reaction of 2,3-dihydrobenzo[b][1,4]dioxine-6- carbaldehyde, various amines, and dimethyl phosphite by using nano-TiO 2 as a catalyst under solvent-free conditions at 50C. The major advantages of the present method are high yields, short reaction times, recyclable catalyst, and solvent-free reaction conditions. Among these new structurally diversified set of alpha-aminophosphonates, dimethyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(3-nitrophenylamino) methylphosphonate and dimethyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(4-fluoro-3-nitro-phenyl-amino) methylphosphonate have shown higher antioxidant activity in diphenyl picryl hydrazyl (DPPH) scavenging, reducing power assay, and lipid peroxidation methods.

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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem