Synthetic Route of 288-14-2, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 288-14-2, Name is Isoxazole,introducing its new discovery.
Several pyridine derivatives containing a biologically active benzenesulfonamide moiety (3-17) were synthesized from the strategic starting material 2-acetylpyridine (1). The structures of the newly synthesized compounds were elucidated on the basis of elemental analysis, IR,1H-NMR13C-NMR and mass spectral data. All the prepared compounds were evaluated for their in vitro anticancer activity against breast cancer cell lines (MCF-7). Most of the synthesized compounds showed good to moderate activity, especially compounds 11, 8, 13, 6, 14, 15 and 9 with IC50 values (23.9, 25.1, 26.6, 28.1, 29.9, 30.4 and 31.4 muM, respectively) which exhibited higher activity than the reference drug doxorubicin with IC50 value (47.9 muM) as positive control. Compounds 10 and 7 are nearly as active as doxorubicin as positive control, while compounds 5, 12, 17, 3 and 4 showed moderate activity. Compounds 18 and 19 exhibited no activity.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 288-14-2, and how the biochemistry of the body works.Synthetic Route of 288-14-2
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem