Simple exploration of 1008-75-9

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1008-75-9, Name is 3-Methyl-5-phenylisoxazole, belongs to isoxazole compound, is a common compound. Safety of 3-Methyl-5-phenylisoxazoleIn an article, once mentioned the new application about 1008-75-9.

A comparative study of reactions of 3-methyl-5-phenylisoxazole and 3-methyl-5-phenylisothiazole with electrophilic compounds in the presence of n-BuLi, LICA or LICA-TMEDA is reported.By using LICA-TMEDA, regioselective reactions of heterocyclic compounds at the C-3 methyl group are obtained.With n-BuLi or LICA and the isoxazole derivative a product mixture at the C-4 position and the C-3 methyl group is found.In the case of isothiazole compound, only with methyl iodide and n-BuLi, the dialkylated product at both positions is formed.

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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem