Brief introduction of 1123-49-5

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Formula: C5H6N2O3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1123-49-5

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Formula: C5H6N2O3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 1123-49-5, Name is 3,5-Dimethyl-4-nitroisoxazole, molecular formula is C5H6N2O3

A series of novel phenylmethylene bis-isoxazolo[4,5-b]azepine derivatives (10) have been synthesized from 3-methyl-4-nitro-5-styrylisoxazoles 6. The reaction of 6 with 3,5-dimethyl-4-nitroisoxazole (7) in piperidine afforded the Michael type adducts 8, which on treatment with different substituted chalcones in the presence of piperidine gave the Michael adducts 9. Compounds 9 underwent reductive cyclization on treatment with SnCl2-MeOH to afford the title compounds 10. Structure of these compounds was established on the basis of IR, 1H NMR, 13C NMR and Mass spectral data. The title compounds 10a-j were evaluated for in vitro and in vivo anticancer activity. Compound 10j exhibited good anticancer activity as that of standard drug Cisplatin.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Formula: C5H6N2O3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1123-49-5

Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem