33282-16-5, 5-(4-Methoxyphenyl)isoxazole-3-carboxylic acid is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a solution of phenylisoxazole acid or phenylpyrazole acid (10a, 10c and 10d) (1 mmol in 30 mL DCM)was added tribromoborane (3 mmol) dropwise under nitrogen at -20C. After the addition, the solution was stirred at room temperature for 24 h. Next, water was added dropwise to this solution until no gas was liberated. The reaction mixture was then extracted with DCM (20 mL ¡Á 2). The organic layer was washed with brine (30 mL ¡Á 2), dried over Na2SO4 and concentrated to obtain a crude demethylated product 10e-g (28% to 49% yields).
33282-16-5, The synthetic route of 33282-16-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Wen, Jiachen; Bao, Yu; Niu, Qun; Liu, Jiang; Yang, Jinyu; Wang, Wanqiao; Jiang, Tao; Fan, Yinbo; Li, Kun; Wang, Jian; Zhao, Linxiang; Liu, Dan; Bioorganic and Medicinal Chemistry Letters; vol. 26; 17; (2016); p. 4372 – 4376;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem