Awesome Chemistry Experiments For Isoxazole

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Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C3H3NO, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 288-14-2

Tin exchanged montmorillonite K10 (SnII-Mont K10) was prepared by ion exchange between SnCl2and montmorillonite K10. The SnII-Mont K10 was characterized by X-ray diffraction, scanning electron microscope and energy-dispersive X-ray spectroscopy. The synthesized SnII-Mont K10 was used as a recoverable solid catalyst for synthesis of 3-methyl-4-arylmethylene isoxazole-5 (4H)-ones via one-pot multicomponent cyclocondensation of hydroxylamine hydrochloride, ethyl acetoacetate and benzaldehyde derivatives in water under ultrasound irradiations. The yields of products were obtained 87?96%. The remarkable advantages of this method are a low-cost and eco-friendliness catalyst, rapid completion of the reactions, and avoidance of using organic solvents, excellent yield and mild conditions.

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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem