1072-67-9, Name is 5-Methylisoxazol-3-amine, belongs to isoxazole compound, is a common compound. Product Details of 1072-67-9In an article, once mentioned the new application about 1072-67-9.
A simple uracil based chemosensor (UraCS) has been developed for sequential detection of Cu2+ and CN? in aqueous acetonitrile solution. The sensor UraCS showed a high selectivity, high sensitivity and quick response to copper ions in the presence of other competing cations including Cd2+, Fe2+, Hg2+, Al3+, Ni2+, Ba2+, Ca2+, Cr3+, Co2+, Zn2+, Cu2+, Pb2+, Ag+, Fe3+ and K+. In the presence of Cu2+, UraCS provided a distinct color change from colorless to dark yellow forming a complex with a 2:1 stoichiometry and reverse color change after addition of CN? to the probe containing UraCS-Cu2+ complex. More importantly, the results confirmed that the UraCS has widely linear detection range of 3.0 to 150 muM toward Cu2+ ions. The calculated limit of detection for Cu2+ ions was low as 0.28 muM. Moreover, interaction of UraCS with Cu2+ causes a significant fluorescence quenching at 378 nm. UraCS-Cu2+ complex could be successfully applied to detect cyanide ions via Cu2+ displacement approach. The free UraCS was recovered after adding the CN? ions in a few seconds due to the formation of the stable copper cyanide complex Cu(CN)x. The DFT calculation was also performed for better understanding of the Cu2+ sensing mechanism. Furthermore, chemosensor UraCS was successfully utilized in the preparation of test strips and supported silica gel for the detection of Cu2+ and CN? ions from aqueous environment and real water samples.
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Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem