Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. HPLC of Formula: C5H7NO2. Introducing a new discovery about 35166-33-7, Name is 3-Hydroxymethyl-5-methylisoxazole
Novel diamino derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists
Piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine have recently been demonstrated to be potent and selective adenosine A 2a receptor antagonists with oral activity in rodent models of Parkinson’s disease. We have replaced the piperazinyl group with a variety of linear, monocyclic, and bicyclic diamines. Of these diamines, (R)-2-(aminomethyl)pyrrolidine is a particularly potent and selective replacement for the piperazinyl group. With this diamine component, we have been able to prepare numerous analogues with low nanomolar affinity toward the A2a receptor and good selectivity with respect to the A1 receptor (> 200-fold in some cases). Selected analogues from this series of [1,2,4]triazolo[1,5-a][1,3,5]triazine have now been shown to be orally active in the mouse catalepsy model.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.HPLC of Formula: C5H7NO2, you can also check out more blogs about35166-33-7
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem