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1008-75-9, Name is 3-Methyl-5-phenylisoxazole, belongs to isoxazole compound, is a common compound. Computed Properties of C10H9NOIn an article, once mentioned the new application about 1008-75-9.
Metal-carbonyl-Induced Reaction of Isoxazoles. Ring Cleavage and Reduction by Hexacarbonylmolybdenum, Pentacarbonyliron, or Nonacarbonyldi-iron
In the presence of and water the isoxazoles (1a-f) undergo thermally induced reductive cleavage of the N-O bond to give beta-amino enones in good yield.Similar results were obtained by the use of and water with photoirradiation, or of and water with heating.A mechanism involving an N-complexed isoxazolepentacarbonylmolybdenum or isoxazoletetracarbonyliron, and a – or -complexed (beta-oxo vinyl)nitrene intermediate is proposed for the reactions.The complexed nitrene moiety could be reduced by the central metal in the presence of water to give amine.Furthermore, treatment of 2-benzoyl- 3-phenyl-2-H-azirine (8a), which is an isomer of 3,5-diphenylisoxazole, with the metal carbonyls and water also resulted in the formation of a beta-amino enone possibly via the corresponding complexed (beta-oxo vinyl)nitrene.An N-complexed isoxazole-pentacarbonylmolybdenum intermediate was prepared by the photoreaction of with 3,5-dimethylisoxazole.Its characterization, and chemical transformations, have been carried out to investigate the proposed mechanism.
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Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem