Can You Really Do Chemisty Experiments About 5-Methylisoxazole-3-carboxylic acid

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Reference of 3405-77-4, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 3405-77-4, Name is 5-Methylisoxazole-3-carboxylic acid,introducing its new discovery.

Scalable, One-Pot, Microwave-Accelerated Tandem Synthesis of Unsymmetrical Urea Derivatives

We report a facile, microwave-accelerated, one-pot tandem synthesis of unsymmetrical ureas via a Curtius rearrangement. In this method, one-pot microwave irradiation of commercially available (hetero)aromatic acids and amines in the presence of diphenylphosphoryl azide enabled extremely rapid (1-5 min) construction of an array of unsymmetrical ureas in good to excellent yields. We demonstrate the utility of our method in the efficient, gram-scale synthesis of key biologically active compounds targeting the cannabinoid 1 and alpha7 nicotinic acetylcholine receptors.

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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem