In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Computed Properties of C10H7NO4, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 33282-15-4, name is 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid. In an article£¬Which mentioned a new discovery about 33282-15-4
Nucleophilic substitution reactions of N-methyl alpha-bromoacetanilides with benzylamines in dimethyl sulfoxide
Kinetic studies of the reactions of N-methyl-Y-a-bromoacetanilides with substituted X-benzylamines have been carried out in dimethyl sulfoxide at 25.0 C. The Hammett plots for substituent X variations in the nucleophiles (log kN vs sigmaX) are slightly biphasic concave upwards/downwards, while the Broensted plots (log kN vs pKa) are biphasic concave downwards with breakpoints at X = H. The Hammett plots for substituent Y variations in the substrates (log kN vs sigmaY) are biphasic concave upwards/downwards with breakpoints at Y = H. The cross-interaction constant pXY values are all negative: pXY = -0.32 for X = Y = electron-donating; -0.22 for X = electron-withdrawing and Y = electron-donating; -1.80 for X = electron-donating and Y = electronwithdrawing; -1.43 for X = Y = electron-withdrawing substituents. Deuterated kinetic isotope effects are primary normal (kH/kD > 1) for Y = electron-donating, while secondary inverse (kH/kD < 1) for Y = electronwithdrawing substituent. The proposed mechanisms of the benzylaminolyses of N-methyl-Y-a-bromoacetanilides are a concerted mechanism with a five membered ring TS involving hydrogen bonding between hydrogen (deuterium) atom in N-H(D) and oxygen atom in C = O for Y = electron-donating, while a concerted mechanism with an enolate-like TS in which the nucleophile attacks the a-carbon for Y = electronwithdrawing substituents. Copyright I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 33282-15-4, help many people in the next few years.Computed Properties of C10H7NO4
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Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem