Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, COA of Formula: C14H17N3O4, 446292-10-0, Name is (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one, SMILES is O=C1N(C2=CC=C(N3C(O[C@@H](CN)C3)=O)C=C2)CCOC1, belongs to Isoxazoles compound. In a document, author is Nurjanah, N., introduce the new discover.
Curcumin Isolation, Synthesis and Characterization of Curcumin Isoxazole Derivative Compound
Curcumin, one of the curcuminoid constituents which derived from Curcuma longa, has been extensively used as a pharmacological agent. This study was started with extraction of the curcuminoid from Curcuma longa where extraction was carried out with two different solvents (dichloromethane and ethanol), followed by isolation of curcumin from the other two components of curcuminoid. The pure curcumin was converted to its isoxazole derivative with the addition of NH2OH center dot HCl. The reaction product was characterized using mass spectrometry, UV/Vis and FTIR spectrophotometry. Optimization of the extraction and synthesis shows that for the extraction ethanol was a better solvent than dichloromethane with 12.67 % yield. Temperature and optimization time for synthesis of curcumin isoxazole were 70 degrees C and 8 hours, respectively.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 446292-10-0. COA of Formula: C14H17N3O4.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem