Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 88-14-2, Name is Furan-2-carboxylic acid, molecular formula is C5H4O3, belongs to Isoxazoles compound, is a common compound. In a patnet, author is El-Mekabaty, Ahmed, once mentioned the new application about 88-14-2, Name: Furan-2-carboxylic acid.
FACILE AND CONVENIENT SYNTHESIS OF NEW ISOXAZOLO[5,4-b]PYRIDINE, PYRROLO[3,2-d]ISOXAZOLE, ISOXAZOLO[5,4-b]AZEPINE-4,7-DIONE AND ISOXAZOLE DERIVATIVES WITH POTENTIAL ANTICANCER ACTIVITY
The readily available 3-methylisoxazol-5-amine (1) has been used as a key intermediate for the synthesis of isoxazolo[5,4-b]pyridine, pyrrolo[3,2-d]isoxazole, isoxazolo[5,4-b]azepine-4,7-dione and isoxazole derivatives via its reactions with some chemical reagents. Sixteen compounds were designed to study their cytotoxic properties against three human cell lines: colorectal carcinoma (HCT-116), prostate cancer (PC3) and normal lung fibroblast (WI-38), using the MTT colorimetric assay. 5-Fluorouracil, a well-known anticancer drug, was used for comparison. Among the tested candidates, pyrrolo[3,2-d]isoxazole 5 and isoxazole derivatives 11-14 showed the highest activity against the tested cancer cell lines with good selectivity by their lower toxicity against normal cells.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 88-14-2. The above is the message from the blog manager. Name: Furan-2-carboxylic acid.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem