In an article, author is Feng, Song, once mentioned the application of 1132-61-2, COA of Formula: C7H15NO4S, Name is MOPS, molecular formula is C7H15NO4S, molecular weight is 209.26, MDL number is MFCD00006183, category is Isoxazoles. Now introduce a scientific discovery about this category.
Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist
According to the docking studies and the analysis of a co-crystal structure of GW4064 with FXR, a series of 3-aryl heterocyclic isoxazole analogs were designed and synthesized. N-Oxide pyridine analog (7b) was identified as a promising FXR agonist with potent binding affinity and good efficacy, supporting our hypothesis that through an additional hydrogen bond interaction between the pyridine substituent of isoxazole analogs and Tyr373 and Ser336 of FXR, binding affinity and functional activity could be improved. (C) 2009 Elsevier Ltd. All rights reserved.
If you are interested in 1132-61-2, you can contact me at any time and look forward to more communication. COA of Formula: C7H15NO4S.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem