168828-90-8, Name is (S)-5-(Aminomethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one, molecular formula is C14H18FN3O3, Formula: C14H18FN3O3, belongs to Isoxazoles compound, is a common compound. In a patnet, author is Shahinshavali, S., once mentioned the new application about 168828-90-8.
Synthesis and Anticancer Activity of Amide Derivatives of 1,2-Isoxazole Combined 1,2,4-Thiadiazole
A series of amide derivatives of 1,2-isoxazole combined with 1,2,4-thiadiazole are synthesized 11a-11j. Their chemical structures are confirmed by H-1 and C-13 NMR, and mass spectra. The products are tested for their anticancer activity against four types of human cancer cell lines, including MCF-7 (breast), A549 (lung), Colo-205 (colon), and A2780 (ovarian). Etoposide is used as a positive control. Most of the compounds show good anticancer activity. The compounds 11b, 11c, 11d, 11e, 11g, and 11j demonstrate more potent activity than etoposide.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 168828-90-8 help many people in the next few years. Formula: C14H18FN3O3.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem