Reference of 42831-50-5, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 42831-50-5, 5-Methylisoxazole-4-carboxylic acid, introducing its new discovery.
A NOVEL PROCESS FOR THE PREPARATION OF TERIFLUNOMIDE
The present invention provides a process for the preparation of Teriflunomide (Formula-I). The present invention describes the synthesis of Teriflunomide without isolating the intermediate Leflunomide. Teriflunomide is prepared from 5-Methyl isoxazole-4-carboxylic acid by converting to its acid chloride and coupling with 4-trifluoromethyl aniline to obtain Leflunomide (which is not isolated) followed by ring opening reaction using aq. Sodium Hydroxide to form Teriflunomide. In other words, the process is telescoped from 5- methylisoxazole-4-carbonyl chloride.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 42831-50-5. In my other articles, you can also check out more blogs about 42831-50-5
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem