Application of 288-14-2, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 288-14-2, Isoxazole, introducing its new discovery.
Synthesis, characterization and biological study of novel quinazolinone derivatives
Condensation of 2-methyl-4H-1,3-benzoxazine-4-one (1) with p-amino acetophenone gave 3-(4-acetylphenyl)-2-methylquinazolin-4(3H)-one(2). Claisen-Schmidt condensation of compound 2 with different aromatic and heterocyclic aldehydes afforded different quinazolyl chalcones 3(a-h) which on refluxing with hydroxylamine hydrochloride gave 3-(4-(5-(3-substitutedphenyl)-4,5-isoxazol-3-yl) phenyl)-2-methyl quinazolin-4(3H)-ones 4 (a-h) in good yields. In anti-convulsant and anti-inflammatory screening, three compounds 4a, 4b & 4f have shown excellent anti-convulsant activity and compounds 4c & 4f showed significant anti-inflammatory activity.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 288-14-2. In my other articles, you can also check out more blogs about 288-14-2
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem