Synthetic Route of 21169-71-1, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 21169-71-1, molcular formula is C4H3NO3, introducing its new discovery.
5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZ1NE DERIVATIVES AS P2X7 MODULATORS
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein A is hydrogen, C1-4 alkyl, C3-6 cycloalkyl, C1-3 alkoxy, C1-3 alkoxy C1-4 alkyl, C1-2 fluoroalkyl, halogen, NR6 R7, optionally substituted heteroaryl (Het), or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis, osteoarthritis or neurodegenerative disorders.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 21169-71-1 is helpful to your research. Synthetic Route of 21169-71-1
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem