Synthetic Route of 33282-15-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.33282-15-4, Name is 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid, molecular formula is C10H7NO4. In a Article£¬once mentioned of 33282-15-4
Ruthenium-catalyzed intramolecular cyclization of diazo-beta-ketoanilides for the synthesis of 3-alkylideneoxindoles
With [Ru(p-cymene)Cl2]2 as catalyst, diazo-beta-ketoanilides would undergo intramolecular carbenoid arene C-H bond functionalization to afford 3-alkylideneoxindoles in up to 92% yields. The reaction occurs under mild conditions and exhibits excellent chemoselectivity. The lack of primary KIE (kH/kD ? 1) suggests that the reaction should not proceed by rate-limiting C-H bond cleavage; a mechanism involving cyclopropanation of the arene is proposed.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 33282-15-4
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem