Synthetic Route of 179162-55-1, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 179162-55-1, 4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoic acid, introducing its new discovery.
Novel echinocandin antifungals. Part 2: Optimization of the side chain of the natural product FR901379. Discovery of micafungin
Further optimization of the potent antifungal activity of side chain analogs of the natural product FR901379 led to the discovery of compound 8 with an excellent, well-balanced profile. Potent compounds with reduced hemolytic potential were designed based upon a disruption of the linearity of the terphenyl lipophilic side chain. The optimized compound (8, FK463, micafungin) displayed the best balance and was selected as the clinical candidate.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 179162-55-1. In my other articles, you can also check out more blogs about 179162-55-1
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem