Simple exploration of 5-Cyclopropylisoxazole-3-carboxylic acid

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110256-15-0, Name is 5-Cyclopropylisoxazole-3-carboxylic acid, belongs to Isoxazoles compound, is a common compound. SDS of cas: 110256-15-0In an article, once mentioned the new application about 110256-15-0.

A new class of bradykinin B1 receptor antagonists with high oral bioavailability and minimal PXR activity

The design and synthesis of a novel class of human bradykinin B1 antagonists featuring difluoroethyl ether and isoxazole carboxamide moieties are disclosed. Compound 7g displayed excellent pharmacokinetic properties, efficient ex vivo receptor occupancy, and low potential for P450 induction via PXR activation.

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Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem