Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Computed Properties of C12H11NO3. Introducing a new discovery about 7063-99-2, Name is Ethyl 5-phenylisoxazole-3-carboxylate
New N-aryl isoxazolecarboxamides and N-isoxazolylbenzamides as anticonvulsant agents
We prepared a series of N-aryl isoxazolecarboxamide, N-isoxazolylbenzamide compounds and derivatives and studied their anticonvulsant action in MES and MMS tests. Some of these reveal considerable activity, especially with respect to MES test. The disubstitution in the 2.6-position on the phenyl ring by two methyl groups would appear to be of primary importance for the activity. The amide bridge between the phenyl and isoxazolic rings, whether of the anilide or benzamide type, seems to show similar anticonvulsant behavior. We have selected the derivatives 8 (N-(2.6-dimethylphenyl)-5-methyl-3-isoxazolecarboxamide, 12 (N-(2.6-dimethylphenyl)-5-hydroxymethyl-3-isoxazolecarboxamide) and 51 (N-(5-methyl-3-isoxazolyl)-2.6-dimethylbenzamide) which are presently being studied in more extended pharmacological tests.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Computed Properties of C12H11NO3, you can also check out more blogs about7063-99-2
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem