14678-05-8, Name is Isoxazol-5-amine, belongs to Isoxazoles compound, is a common compound. name: Isoxazol-5-amineIn an article, once mentioned the new application about 14678-05-8.
Selective access to dipyrazolo-fused pyridines: Via formal [3 + 2 + 1] heteroannulation of methyl ketones with pyrazol-5-amines
A fascinating new form of the Hantzsch reaction with methyl ketones and pyrazol-5-amines for the selective synthesis of dipyrazolo-fused pyridines has been discovered. This special [3 + 2 + 1] heteroannulation was accomplished via the domino generation of two C-C bonds and one C-N bond. Preliminary mechanistic studies indicated that the I2/DMSO system realized the oxidative carbonylation of Csp3-H of methyl ketones, while Cu(OTf)2 acted as a relay reagent to accelerate this transformation.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 14678-05-8
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem