33282-15-4, Name is 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid, belongs to Isoxazoles compound, is a common compound. SDS of cas: 33282-15-4In an article, once mentioned the new application about 33282-15-4.
BASICITY OF NITROGEN-SULPHUR(VI) COMPOUNDS. PART 5. IONIZATION OF TRISUBSTITUTED SULPHAMIDES
The ionization equilibria in base of 27 trisubstituted sulphamides, mainly represented by the following series: X-C6H4NHSO2NR2R1, where NR2R1=piperidyl, morpholinyl, and NnPr2, and RHNSO2NR2R1, where R,R1, and R2 are cyclo-C6H11, Ac, and X-C6H4 and X-C6H4, Ac and X-C6H4, have been studied in 60percent v/v ethanol-water using the potentiometric method.In a few cases pKa values have been determined by u.v. method.The effect of substituents has been correlated in Hammett plots and values are generally ca. 2.6 (as an for aryl linked nitrogen in sulphonanilide ionizations).The acid-strengthening effect of the acetyl group and the acid-weakening effect of the methyl group are seen in some series.
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Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem