In heterogeneous catalysis, the catalyst is in a different phase from the reactants. COA of Formula: C5H5NO3, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 3405-77-4, name is 5-Methylisoxazole-3-carboxylic acid. In an article£¬Which mentioned a new discovery about 3405-77-4
4-Iminooxazolidin-2-one as a Bioisostere of the Cyanohydrin Moiety: Inhibitors of Enterovirus 71 3C Protease
A recently reported potent inhibitor of enterovirus 71 3C protease, (R)-1, was found to have stability and potential toxicity issues due to the presence of a cyanohydrin moiety. Modifying the labile cyanohydrin moiety, by serendipity, led to the discovery of 4-iminooxazolidin-2-one-based inhibitors 4e and 4g with potent inhibitory activity and significantly improved stability. In vivo pharmacokinetic studies of 4e also demonstrated high plasma exposure and moderate half-life. These compounds have shown potential of becoming anti-EV71 drug candidates.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 3405-77-4, help many people in the next few years.COA of Formula: C5H5NO3
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem